Highlights
Thank you for attending our webinar:
Distance Learning for Cell Biology webinar
Distance Learning for Cell Biology webinar
|
Distance Learning for Cell Biology: A virtual laboratory for teaching Mitosis (recorded April 14th, 2020)
As part of our mission to support open science, the Allen Institute shares all of the data we generate freely for anyone to use in research or teaching. This enables students to conduct online experiments for distance learning. In this webinar, you’ll learn how to run a ready-to-use, fully online virtual lab experiment with your students. |
|
COVID-19 update
To minimize risk of transmission of COVID-19 among employees and to meet Washington state mandates, we activated a work from home policy for non-essential employees, effective March 6th.
While our experimental program is compromised, all of our other activities continue uninhibited and we remain open for science. Our cell lines and plasmids are still available from Coriell and Addgene, respectively. Our computational analysis tools and visualization platforms can be viewed and utilized by researchers and educators here on allencell.org.
If your laboratory is working on COVID-19 research, and you think any of our resources might help you, please let us know at cells@alleninstitute.org.
While our experimental program is compromised, all of our other activities continue uninhibited and we remain open for science. Our cell lines and plasmids are still available from Coriell and Addgene, respectively. Our computational analysis tools and visualization platforms can be viewed and utilized by researchers and educators here on allencell.org.
If your laboratory is working on COVID-19 research, and you think any of our resources might help you, please let us know at cells@alleninstitute.org.
|
Educational Resources on allencell.org
Many educators have incorporated data, tools, and information they found on allencell.org into how they teach biology.
Learn how three educators use these resources, and incorporate a step-by-step virtual laboratory on cell division, published in CourseSource, into your classroom. |
|
New resources to access mitotic stem cell states & endogenously tagged cardiomyocytes
|
|
|
Integrated Mitotic Stem Cell
A model & visualization tool to better understand how stem cells divide |
The new lines include a triple-edited line labeling all three nucleolar subcompartments and a single-edited line visualizing mitochondrial nucleoids.
|
We present the Allen Cell Structure Segmenter, a python-based, open-source toolkit that combines classic 3D image segmentation with artificial intelligence to detect cellular structures.
Read more about this new toolkit and how it can help biologists analyze their 3D images of cells and be more quantitative with their results. |
|
Previous highlights
|
A visual essay on the Integrated Mitotic Stem Cell
We present the Integrated Mitotic Stem Cell as a data driven model and visualization tool that captures a holistic view of human cell division for the first time.
By enabling a deeper understanding of how healthy human cells divide, the model will further basic biology research as well as studies of cancer, a disease that often results from cell division gone awry. |
|
Visual Guide to Human Cells
This visual guide organizes information about human induced pluripotent stem cells into a curated collection of interactive models. Users can rotate and zoom into 3D cells, each segmented from real data for each phase of mitosis, while learning more about individual cell structures and functions.
|
|
Label-free Determination
As part of the Allen Integrated Cell, we have developed and implemented a label-free prediction method for determining the location of 3D structures inside the cell, directly from transmitted light images.
|
|
Videos & tutorials
Instructional videos provided to ensure success in your lab & to overview tools available on allencell.org
Cells & plasmids for your lab
We have created a series of gene edited human iPSCs that we use as the foundation for our image data, and that we share with the larger scientific community.
|
Obtain cell lines & plasmids for your lab; quality control details
|
Explore & download genomics & transcriptomics data
|
Step-by-step protocols to generate & image gene-edited hiPSCs successfully
|
Research Projects described
|
Observations describing effects of drugs on 3D cellular organization
|
Multiple cell structures visualized direct from brightfield imaging
|
3D visualization of hIPS cell structure variation
|
