A human induced pluripotent stem cell model for the holistic study of epithelial-to-mesenchymal transitions This study presents an human induced pluripotent stem-cell-based culture model for studying cell state transitions during epithelial-to-mesenchymal transition.
Read publication Search, organize, aggregate & share image data with BioFile Finder "Finding the right image data can be surprisingly difficult, especially across large, siloed and inconsistently labeled datasets. As biological imaging grows in scale and collaboration, most laboratories routinely record some metadata alongside acquisition, but these annotations are often sparse and fragmented across filenames, spreadsheets or unstructured notes, making datasets difficult to search or interpret in practice. As a result, the field increasingly requires tools that make it easier to find, explore, reuse and share data.
We developed BioFile Finder (BFF) to address this gap: a free, easy-to-use, open-source application that transforms a simple spreadsheet of image metadata describing what is interesting or important about each image file into an interactive, searchable, and browsable dataset (https://bff.allencell.org)." Read publication  Dec 6 - 10, 2025 | Philadelphia, PA
BOOTH --------------------------------------------------------------------------------------------------------------------------- #1125 Allen Institute scientists and staff will be on hand to answer all of your questions about our research, open data, and online tools. Sunday, December 7 - Tuesday, December 9, 2025 | 9:30am-4:00pm EST daily TALK ----------------------------------------------------------------------------------------------------------------------------- Nuclear morphogenesis reflects both cell lineage and environmental context in 2D and 3D hiPS cell models by Leigh Harris Saturday, December 6, 2025 | 10:00-12:00pm EST Opening the AI black box to enhance the creativity of cell biologists by Susanne Rafelski Sunday, December 7, 2025 | 5:30-6:45pm EST A dynamical systems framework applied to live cell imaging of hiPSC-derived endothelial-like cells under flow uncovers a first-order phase transition between morphology-based cell states by Serge Parent Wednesday, December 10, 2025 | 9:15-9:30pm EST TECH TALK ---------------------------------------------------------------------------------------------------------------------- BioFile Finder (BFF): an easy-to-use, web-based solution for sharing image data & increasing transparency by Caroline Hookway and Gideon Dunster Sunday, December 7, 2025 | 1:15-2:00pm EST POSTER -------------------------------------------------------------------------------------------------------------------------- Adherent hiPSC lumenoids: A robust 3D platform for bridging cellular dynamics and multicellular organization by Leigh Harris Sunday, December 7, 2025 | 12:45-3:45pm EST A dynamical systems framework applied to live cell imaging of hiPSC-derived endothelial-like cells under flow uncovers a first-order phase transition between morphology-based cell states by Serge Parent Monday, December 8, 2025 | 2:15-3:45pm EST Developmental and Stem Cell Biology - Stem cell identity, Pluripotency, and Differentiation by Caroline Hookway Tuesday, December 9, 2025 | 12:45-2:15pm EST EDUCATION SESSION ---------------------------------------------------------------------------------------------------------- by Kaitlyn Casimo and Gideon Dunster Tuesday, December 9, 2025 | 5:30-6:30pm EST For 10 years, the cell science accelerator at Allen Institute has been a leader in accelerating advancements in cell biology. By creating groundbreaking tools, resources, and open-access datasets and models, the Institute has empowered researchers and educators to explore and understand cells in new ways. Through its large-scale, interdisciplinary efforts, it has enabled the scientific community to tackle complex biological questions and make discoveries that wouldn’t be possible otherwise.
 When: Dec 14 - 18, 2024
Where: San Diego, California Visit exhibit hall booth #313 to meet researchers, educators, and recruiting staff from the cell science accelerator at Allen Institute and learn about our open science resources & career opportunities. Explore our datasets, visualization tools, software, and human iPS cell lines available on the Allen Cell Explorer. We just released 8 disease cell line collections, each containing multiple isogenic control and mutation-carrying clones:
 "Cell states were traditionally defined by how they looked, where they were located, and what functions they performed. In this post-genomic era, the field is largely focused on a molecular view of cell state. Moving forward, we anticipate that the observables used to define cell states will evolve again as single-cell imaging and analytics are advancing at a breakneck pace via the collection of large-scale, systematic cell image datasets and the application of quantitative image-based data science methods. This is, therefore, a key moment in the arc of cell biological research to develop approaches that integrate the spatiotemporal observables of the physical structure and organization of the cell with molecular observables toward the concept of a holistic cell state. In this perspective, we propose a conceptual framework for holistic cell states and state transitions that is data-driven, practical, and useful to enable integrative analyses and modeling across many data types."
We are excited to host the 11th EMT International Association (TEMTIA 11) meeting at the Allen Institute in Seattle, Washington, USA, on November 12-15, 2024.  The epithelial to mesenchymal transition (EMT) is a cell state change during which cells transition from stationary to migratory behavior. Associated with normal development but also a characteristic of many cancers, EMT includes complex changes across multiple cell characteristics and is consistently and universally difficult to define. At this year’s TEMTIA, we will leverage the diversity of the field, convening experts across contexts, perspectives, and scales of study to address this challenge. Scientific sessions will be organized with common themes such as: data integration, microscopy in EMT, modeling of state changes, and more.
To recognize the seminal contributions of Dr. Elizabeth Hay to the EMT field, TEMTIA will present the Betty Hay award of AU$1000.00 to a young female scientist. To apply for the fellowship or for more information, visit the Event Details page. Talk/poster abstract submission deadline: May 31, 2024 Please contact [email protected] for any questions.  Meet scientists from the Allen Institute for Cell Science, learn about our open resources and updates on our scientific researches, talk to our recruiting team about career opportunities, and more at the 2023 Annual Meeting of the Biophysical Society (BPS).
Date: February 10-14, 2024 Location: Philadelphia, Pennsylvania Booth #301 Happy Holidays from all of us at the Allen Institute for Cell Science!  |
OverviewTo receive the Allen Institute e-newsletter, sign up here. Archives
December 2025
Categories |
RSS Feed
We accelerate foundational research, catalyze bold ideas, develop tools and models, and openly share our science to make a broad, transformational impact on the world.
_
|
© 2026 allen institute. all rights reserved.
|